PlasmaGenesis- Epidermal Treatments


Bright closeup portrait of beautiful woman with skin crops. Skincare concept

Epidermal Changes with Age
As we age, the skin cell turnover declines which lead to the visible signs of skin surface aging. Accumulation of old, worn out cells on the surface results in dull, lustreless skin, with uneven pigmentation and rough, leathery texture. A decrease in cell turnover also leads to less hydration in the skin. The ability of our skin to retain moisture is dependent on the key lipids within the surface layers of the skin. These lipids are manufactured as we break down skin surface cells in the process of keratinization, hence drier, rougher, thinner skin with a decrease in cell turnover.  Fewer lipids, along with less keratin and damaged cells lead to poor skin protection which makes us more sensitive to environmental influences such as the sun, cold, dry air, and any of the cosmetic treatments.

Signs of Epidermal Aging:

  • Dull, lustreless skin
  • Rough skin texture
  • Uneven pigmentation
  • Fine lines

Cosmetic Treatments for Epidermal Aging:

  • Microdermabrasion
  • Chemical peels
  • Micropen
  • CO2 Fractional Laser Resurfacing

Microdermabrasion and chemical peels are for mild and early epidermal changes and for preventive and maintenance goals

We use PlasmaGenesis with Micropen and CO2 Fractional Laser resurfacing so you can get the most from your Micropen and CO2 laser skin treatment.


Our patient, before and after two PlasmaGenesis with Micropen treatments, individual response varies

PlasmaGenesis with Micropen:

Plasmagenesis harnesses the healing ability of your blood to regenerate healthy new tissue in the treatment area for a natural improvement via platelet-derived growth factors.

Micropen involves gently resurfacing the top layers of the skin with a device that uses a special tip equipped with surgical steel microneedles. A medical grade Micropen device has a very efficient oscillatory function so that the needles vibrate at 6000-8000 rpm during your skin resurfacing to minimize trauma. The resurfacing of surface skin cells and recurrent needle punctures from the Micropen treatments, lead to micro injuries and a controlled inflammatory response in your skin. Your body responds by collagen synthesis, hence the term, Collagen Induction Therapy or CIT.

A series of Micropen treatments is needed for most cosmetic improvements, the number of treatment varies for the condition being treated, the area of treatment and your individual response.

For PlasmaGenesis of the epidermis, to get the most benefit from your platelet derived growth factors, your Platelet Rich Plasma (PRP) is injected into the epidermis and dermis along wit the topical application. The quality of PRP, the injection technique, your preparation for the PRP treatment are all important in the final outcome of the treatment.

PlasmaGensis with Micropen for Epidermal Treatments is recommended for:

  • Mild to moderate epidermal aging
  • Mild to moderate depth acne scars
  • Stretch marks of mild to moderate depth
  • Deeper scars in dark skin, when CO2 fractional laser may induce PIP (post inflammatory pigmentation)
  • Those individuals who are unable to take time off to recover from the CO2 fractional laser
  • Thos who have any other contraindication to the CO2 fractional laser

Our patient, before and after DOT CO2 fractional laser resurfacing, individual response varies

PlasmaGenesis with CO2 Fractional Laser Resurfacing

DOT Therapy (Dermal Optical Thermolysis) with the Smartxide CO2 fractional laser offers an excellent laser skin resurfacing treatment option for men and women of all ages. The DOT therapy is effective in improving deep wrinkles, skin texture, sun pigmentation, acne scars and stretch marks.

How is DOT Therapy Different from the Micropen?

DOT therapy with CO2 fractional laser is considerably more invasive than the Micropen and can lead to significant improvement in fine & deep wrinkles, texture, sun-induced pigment changes, acne and other scars and stretch marks. Being more invasive means a little more discomfort and more downtime following the DOT therapy. We recommend DOT therapy for moderate to severe epidermal aging and mild dermal aging since DOT therapy can be adjusted to include deeper skin layers than Micropen alone. Here are some of the skin conditions that have excellent improvement with the DOT therapy Co2 fractional laser resurfacing:

  • Photoaging
  • Fine & deep lines around the mouth or “Smoker’s lines”
  • Crow’s feet
  • Age spots
  • Moderate depth acne or other scars
  • Large pores
  • Stretch marks that developed during puberty or pregnancy
  • Droopy or heavy eyelids- the “madonnalift”

PlasmaGenesis with DOT CO2 Fractional Laser

Autologous platelet-rich plasma (PRP) derived from whole blood is immunologically inert and contains a proper ratio of growth factors and cytokines. Combining PlasmaGenesis PRP injection therapy with DOT CO2 laser resurfacing leads to a remarkably better outcome from the laser for any of the above skin conditions due to the healthy tissue regeneration boost from the Platelet-derived growth factors. For mild to moderate photoaging, one moderate depth DOT therapy is sufficient, for deeper wrinkles and scars, more than one treatment is needed to obtain the desired results.

Call 888-210-9693 or email for a consultation in Dallas or Southlake to find out which PlasmaGenesis epidermal treatment is right for you.

Clinical Research PRP & CO2 Fractional Laser

Arch Aesthetic Plast Surg. 2016 Feb;22(1):40-44. English.
Published online February 29, 2016.
Copyright © 2016 Korean Society for Aesthetic Plastic Surgery
The Effectiveness of Ablative Fractional Carbon Dioxide Laser with Autologous Platelet Rich Plasma Combined Resurfacing for Hypertrophic Scar of the Shoulder
DaWoon Lee,1 Eun Soo Park,1 Min Sung Tak,2 and Seung Min Nam1
1Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine, Bucheon, Korea.
2Department of Plastic and Reconstructive Surgery, Soonchunhyang University Seoul Hospital, Seoul, Korea.